Anionic Polymer-Modified Electrodes Based on a Macrocyclic Nickel(II) Complex for Selective Determination of Dopamine in the Presence of Ascorbic Acid

摘要

Selectivity,in addition to sensitivity,is of great interest in the electrochemical determination of compounds in biological samples.Dopamine (DA),a catecholamine neurotransmitter,exists in the brain,blood plasma,and urine,and is involved in diseases such as Parkinson's.In biological samples,DA occurs with relatively higher concentrations of ascorbic acid (AA).When DA is oxidized to DA quinone,AA is oxidized at a similar potential to DA at ordinary solid electrodes,which decreases the electrodes' selectivity for DA.