Simple Ratiometric Fluorophore for the Selective Detection of Mercury through Hg(II)-Mediated Oxazole Formation

摘要

A simple propargylamide-fuctionalized chemodosimeter was prepared for the ratiometric fluorescence detection of mercuric ions in HEPES buffer. The chemodosimeter exhibited Hg~(2+)-induced propargyl amide-to-oxazole transformation, with a significant accompanying ratiometric change in fluorescence. It afforded high selectivity for mercuric ion detection without any competitive inhibition by common alkali, alkaline earth, or other transition metal ions. The probe showed a 17 x 10~(-6) M detection limit for Hg~(2+) ions and potential applicability for detecting aqueous Hg~(2+) ions.