Concise Synthesis of Stemofurans A, C, and Derivatives

摘要

Stemofurans A-F (1-6) are isolated from Stemona colli-nsae, S. tuberose, and S. peirrei, which are mainly distributed in southeast Asia (Fig. 1). These plants have been used in traditional Asian medical practices for the treatment of inflammatory-related diseases. The dried root tuber of these plants, "baibu", is listed in the Chinese pharmacopoeia and used to relieve cough. These plants are also used as antiasthmatics in Vietnamese folk medicine. Furthermore, compounds isolated from these plants have shown to possess antifungal and antibacterial activities, as well as inhibition properties of leukotriene formation.