A Palladium Metalloreceptor with Two 5-Amino-3H-1,3,4-thiadiazolin-2-one Groups

摘要

As part of an ongoing study of metalloreceptors composed of two 5-amino-3H-1,3,4-thiadiazolin-2-one moieties and a 1,3-benzenedimethanethiol subunit, this study describes the synthesis of a metalloreceptor boasting a cavity size amenable to molecular recognition of DNA/RNA nucleo-bases, including cytosine, adenine, and thymine as well as imidazole, pyrazine, and 2,6-dimethylpyrazine. Both the synthesis and characteristics of molecular recognition were as described in previous reports.