3D Cell Culture: Advanced Translational Cell Research: A Reduction to Practice

摘要

The use of in vitro cell based assays has become commonplace in both academic and industrial research sectors. The acceptance of these has been largely due to their demonstrable utility as both drug-discovery and basic research tools. In recent times, we have observed a shift toward more biologically relevant approaches. Currently, the biggest driver in the field is to improve the relevance of cellular assays. To achieve this many are turning their attention to the use of primary cells and/or 3 dimensional cellular models. In this chapter we will discuss our current approach in this area.