Laser Magnetic Resonance Spectroscopy: Fundamental Physics to Medical Analysis of Free Radicals

摘要

Laser magnetic resonance spectroscopy offers a profoundly sensitive and illuminating technique for the study of open-shell molecules, allowing the precise determination of high-order quantum mechanical magnetic effects, as well as a sensitive and discriminating tool for biomedical analysis. Laser magnetic resonance (LMR) spectroscopy was developed in 1968 by Evenson and co-workers [1]. The method was among the first implementations of laser spectroscopy in the far-infrared (FIR) region of the spectrum (10-500 cm~(-1)), home to the simplest rotational spectra of the diatomic hydrides. It remains an enduring technique for the study of free radicals by virtue of its exceptional sensitivity and discrimination against closed-shell species.