Dietary n-3 fatty acids reduce the delayed hypersensitivity reactio and antibody production more than n-6 fatty acids in brolier birds

摘要

The splenocyte fatty acid profile and immune response of broiler chickens were investigated.One hundred nad twenty ady-old broiler chicks were fed diets containing conjugated linoleic acid (CLA)(Diet I),sunflower oil (DietII),flaxseed oil (Diet III)or fish oil (DietIV),The total lipid content of the diets was 3.5%.bBirds fed diet iii and iv had a higher content of n-3 fatty acids in splenocytes than those fed diets I and II.serum anti-Bsa immunoglobulin content was higher (P<0.05)i birds fed diets III and IV,compared to those fed diets I and II,Delayed type hypersensitivity response,measured as teh wing web skin weelling reactin (thickness)to mycobacterium butyricum injection (s.c),increased (p<0.05)from 0.71 and 0.98 mm in diets IV and III,respectively,to 1.19 adn 1.41 mm in diets i and II,respectively.The number of CD4~+ and CD8~+ blood lymphocytes and CD4~+,cd8~+ and IgM~+ Splenocytes did not differ (P>0.05)between treatment groups.N-3 fatty acids increased production performances and antibody meditated responses,while n-6 fatty acids and conjugated linoleic acid increased cell mediated responses in broiler birds.