Ammonium Acetate: An Efficient Reagent for the One-pot Synthesis of 5-Aryl-7,8,13,14-tetrahydrodibenzo [a,i]phenanthridines, 2,4-Diaryl-6,7-benzo-3-azabicyclo[3.3,1]nonan-9-ones and α,α'-Bis(substituted benzylidene)cycloalkanones

摘要

The condensation of cyclic ketone with aromatic aldehydes in the presence of ammonium acetate under ethanol media affords the corresponding 5-aryl-7,8,13,14-tetrahydrodibenzo[a,i]phenanthridine with excellent yield. This mild and efficient procedure with high yield is also applied to the synthesis of 2,4-diaryl-6,7-benzo-3-azabicyclo-[3.3.1]nonan-9-ones and α,α'-bis(substituted benzylidene)cycloalkanones.