One-Pot Synthesis of 1,2,3-Triazoles from Michael Reaction

摘要

1,2,3-Triazoles,which can be readily prepared from click chemistry,are important building components that could be exploited in many applications in organic,organometallic,and medicinal chemistry,as well as in materials chemistry.Click chemistry is increasingly being used in medicinal chemistry research.Because it enables a modular approach to pharmacophores,it is finding applications ranging from lead discovery and optimization to the tagging of biological systems such as proteins,nucleotides and whole organisms.