Inverse Eeantioselectivity with Catalyst Loading in Enantioselective Self-Benzoin Condensation using Triazolium-based iV-Heterocyclic Carbene Catalyst

摘要

Asymmetric organocatalysis is a rapidly growing and important field of organic chemistry.N-heterocyclic carbenes (NHCs), which are Lewis base catalysts, represent a versatile class of organocatalysts that allow the addition of a variety of different electrophiles to carbonyl or Michael acceptors via Umpolung or Breslow intermediates.