CRISPR Works Well but Needs Upgrades

摘要

The gene-editing technology known as CRISPR-Cas9 went through a disruptive phase when it first took the research world by storm.Now, thousands of research articles later, it is starting to raise expectations in the therapeutic realm. In fact, CRISPR-Cas9 and other CRISPR systems are moving so close to therapeutic uses that the technology's ethical implications are starting to attract notice. For example, people worry that CRISPR could be used to alter human germ-line cells, introducing genomic changes that could impact future generations.