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To Kill Cancer, Don't Repress It, Excite It

机译:杀死癌症,不要压抑,兴奋

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摘要

The momentum of a cancer's attack can be used against the cancer, say scientists who practice a form of molecular judo. Instead of directly blocking the action of cancer-causing genes, the scientists use this action against cancer cells, throwing themoff balance. Committed to a super-stimulated state, cancer genes can't help but generate a super-abundance of proteins, which pile up, unfolded, overwhelming the cancer cells' protein-processing machinery, triggering a stress response, and—finally—bringing the cancer cells down.
机译:实践一种分子柔道的科学家说,癌症发作的动力可以用来抵抗癌症。科学家没有直接阻止致癌基因的作用,而是利用这种作用来对抗癌细胞,使它们失去平衡。致癌基因处于超级刺激状态,它不禁产生大量的蛋白质,这些蛋白质堆积,展开,压倒了癌细胞的蛋白质加工机制,引发了应激反应,并最终带来了癌细胞下降。

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