Studies on the Total Synthesis of Amphidinolide O (IV): A Stereoselective Synthesis of C1-C11 Fragment

摘要

The amphidinolides are well-known series of cytotoxic macrolides isolated from the marine dinoflagellate Amphidinium sp., which is a symbiotic with Okinawan marine flatworm Amphiscolops sp., and attracted interests from the synthetic community due to their potent cytotoxic activities against various cancer cell lines.