A Simple Phenol-Indole Dye as a Chromogenic Probe for the Ratiometric Determination of Water Content in Organic Solvents

摘要

A simple dye having phenol and indole moieties was synthesized and its chromogenic signaling behaviors for the determination of water content in organic solvents were investigated. The compound revealed a pronounced chromogenic behavior in response to the variation of water content in water miscible aprotic organic solvents of acetone, ace-tonitrile, THF, and dioxane. Significant red shifts and changes in absorption spectra allowed a ratiometric analysis of the signaling behavior. The chemosensing behaviors were particularly pronounced in water content in less than 10% that is suitable for the application of the compound as a probe for the determination of water content in binary aqueous organic solutions having lower water content.