Hydrolysis of Phosphate Esters Mediated by New Unsymmetrical BinuclearCu Complex

摘要

There have been considerable research efforts in developing efficient catalysts carrying two or three metal ions for the hydrolysis of phosphate esters. It might be unnecessary to place two metal ions in close proximity by using metal binding functional groups. Recently some Zn and Cu complexes of binuclear ligands have shown moderate to enormous rate enhancements in cleaving phosphate esters.2 Binuclear Cu and Zn complexes of l,3-di(1,5,9-triaza-cyclododecan-1-yl)propane in methanol turned out to be far the most efficient catalyst in cleaving 2-hydroxypropyl-p-nitrophenyl phosphate (HPNPP) through the substrate bridging to both metal ions.