Synthesis of 4-Benzylidene-2,5-dimethyl-3,4-dihydro-2H-pyrrole Derivatives from Baylis-Hillman Adducts and Their Chemical Transformations

摘要

Recently,Basavaiah and Rao reported the synthesis of substituted gamma-lactams by the reductive cyclization of gamma-nitroesters,which were prepared from the reaction of the acetates of Baylis-Hillman adducts and nitro compounds.gamma-Nitrocarbonyl compounds could be transformed into cyclic nitrones or pyrroline derivatives depending upon the reduction conditions and the nature of the carbonyl groups.