Efficient and Selective Debromination of vic-Dibromides to Alkenes UsingCoCl2·6H2O/Indium System

摘要

The combination of halogenation and reductive dehalo-genation is a useful step in the double bond protection-deprotection strategy. Reductive debromination of vic-dibromides with a variety of different agents has been the subject of many reports. However, most methods lack the desired chemoselectivity when other reducible flinctional groups are present and often require prolonged reaction times, or involve harsh reaction conditions.