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Capillary Electrophoresis with Nanoparticle Matrix for DNA Analysis

机译:纳米颗粒毛细管电泳用于DNA分析

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摘要

Biopolymer such as DNA is important in living cells since its genetic information provides many building blocks for cell components.Also,DNA is employed for diagnosis of genetic disease,DNA sequencing,forensic investigation,and post-human genome project.Conventional methods such as slab gel electrophoresis (SGE) and ion chromatography (IC) for DNA analysis suffered long separation time and low resolution.However,recently developed capillary gel electrophoresis (CGE) showed high speed and high separation efficiency for especially DNA separation.
机译:DNA之类的生物聚合物在活细胞中非常重要,因为其遗传信息为细胞成分提供了许多构建基块。此外,DNA还被用于遗传疾病的诊断,DNA测序,法医研究以及人类后基因组计划。平板等常规方法用于DNA分析的凝胶电泳(SGE)和离子色谱(IC)分离时间长且分离度低。然而,最近开发的毛细管凝胶电泳(CGE)表现出高速度和高分离效率,尤其是DNA分离。

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