A Concise Synthesis of 8-Oxoberberine and Oxychelerythrine, Natural Isoquinoline Alkaloids through Biomimetic Synthetic Way

摘要

Natural isoquinoline alkaloids such as berberine and chelerythrine exhibit a variety of biological activities. Berberine has been isolated from several medicinal herbs, such as Hydrastis canadensis,Cortex phellodendri and Rhizoma coptidis which are widely distributed in plants and used as the traditional oriental medicine.