Oxidation of N-Methylanilines by a Nonheme Iron(IV)-Oxo Complex

摘要

High-valent iron-oxo species have been frequently employed in heme and nonheme iron enzymes to carry out catalytic oxygenation reactions. In heme-based systems, biological and synthetic oxoiron(IV) porphyrin pi-cation radicals are believed to carry out the catalytic oxidations of organic substrates. In the nonheme iron enzymes, oxoiron(IV) intermediates have recently been identified by spectroscopic methods in the catalytic cycle of taurine dioxygenase, and synthetic nonheme oxoiron(IV) species bearing tetradentate and pentadentate ligands were also isolated and characterized. In addition, it has been demonstrated that the nonheme oxoiron(IV) species were capable of conducting the conversion of diverse organic subsatrates such as PPh3, thioanisole, alcohol, and alkanes.