Two New Diarylheptanoids from Juglans mandshurica

摘要

The roots of Juglans mandshurica Maximowicz (Juglandaceae) have been used as a folk medicine for the treatment of cancer in Korea.Several naphthoquinones,naphthalenyl glucosides,tetralones,flavonoids,diarylhepta-noid and galloyl glycosides have been isolated from Juglans species,and these compounds have been shown cytotoxic activity,topoisomerases I and II inhibitory activity,inhibitory effect on DNA polymerase and on the RNase H activity of HIV-1 reverse transcriptase.