A Practical and Simple Method of Recycling Catalyst in Asymmetric Aminohydroxylation of Olefins

摘要

The Os-catalyzed asymmetric aminohydroxylation (AA) of olefins provides a straightforward method for the enantio-selective synthesis of a wide variety of protected vicinal aminoalcohols.The resulting chiral beta-aminoalcohols group is the most abundant structural element in many biologically active molecules as well as the starting point in the design of many chiral ligands.