An Efficient Total Synthesis of Mulberrofuran B and L

摘要

An efficient approach has been developed for the synthesis of mulberrofuran B and L from 2,4-dihydroxybenzaldehyde and 5-bromoresorcinol. The key steps of the synthesis are neutral Al2O3 -mediated regioselective geranylation, Ramirez gem-dibromoolefination, and the Suzuki coupling.