Highly Efficient Acidic Etherification Using a Trichloroacetimidate for the Preparation of (4-Chlorophenyl)(2-pyridyl)methyl-4-piperidyl Ether, a Key Intermediate of Bepotastine

Kim Soo Jeong; Oh Youree; Park HoonGyu; Oh Sehan; Kim Hakwon

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Highly Efficient Acidic Etherification Using a Trichloroacetimidate for the Preparation of (4-Chlorophenyl)(2-pyridyl)methyl-4-piperidyl Ether, a Key Intermediate of Bepotastine

机译：使用三氯乙酰亚胺酸进行高效酸化醚化，以制备（4-氯苯基）（2-吡啶基）甲基-4-哌啶醚（贝托帕斯汀的关键中间体）

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来源
《Bulletin of the Korean Chemical Society》 |2015年第7期|共3页
作者
Kim Soo Jeong; Oh Youree; Park HoonGyu; Oh Sehan; Kim Hakwon;
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原文格式 PDF
正文语种 eng
中图分类化学;
关键词
Bepotastine; Antiallergic drug; Acidic etherification; Trichloroacetimidate;

机译：倍他汀;抗过敏药;酸性醚化;三氯乙酰亚胺;

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1. Highly Efficient Acidic Etherification Using a Trichloroacetimidate for the Preparation of (4-Chlorophenyl)(2-pyridyl)methyl-4-piperidyl Ether, a Key Intermediate of Bepotastine [J] . Kim Soo Jeong, Oh Youree, Park HoonGyu, Bulletin of the Korean Chemical Society . 2015,第7期

机译：使用三氯乙酰亚胺酸进行高效酸化醚化，以制备（4-氯苯基）（2-吡啶基）甲基-4-哌啶醚（贝托帕斯汀的关键中间体）
2. Preparation of (2E,4E)-2-(2-benzyloxyethyl)-5-(3-methoxy- 4-chlorophenyl)penta-2,4-dienal as a key intermediate in the synthesis of strobilurin B [J] . V. A. Popovsky, A. V. Stepanov, N. Ya. Grigorieva Russian Chemical Bulletin . 2012,第8期

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机译：有效合成6-羟基4-（4-氯苯基）-2,2-二甲基-7-苯基-2,3-二羟基-1H-吡咯嗪的关键中间体
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机译：面向药物开发的绿色技术：I.合成功能不同的对苯二酚作为重要的药物中间体。二。在绿色化学中的应用：在中性条件下对芳族醚进行环境友好的裂解和反式醚化。三，硝基化合物的环保简单酰胺化：对乙酰氨基酚的一步合成。
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Highly Efficient Acidic Etherification Using a Trichloroacetimidate for the Preparation of (4-Chlorophenyl)(2-pyridyl)methyl-4-piperidyl Ether, a Key Intermediate of Bepotastine

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