At this year's annual Cold Spring Harbor Laboratory genome meeting, entitled 'The Biology of Genomes', the focus was progress in the emerging field of high-throughput functional biology. All the major players in the genomics field were in attendance,and the cover of the abstract book depicted them as the lords of the (DNA) ring. Genomics is clearly moving from its initial 'structural' phase (sequencing) into a functional phase. Three broad research directions showed particular promise, and some of the significant progress is summarized here.
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