Genome informatics: taming the avalanche of genomic data

摘要

The pace of genomic data generation has recently accelerated substantially, particularly for higher eukaryotes. The genome sequences of more than a dozen multicellular eukaryotes are now finished, and complementary information such as expressed sequence tags (ESTs), and data on gene expression, protein-protein interactions, single-nucleotide polymorphisms (SNPs) and proteomics are being generated in high-throughput mode. To make sense of this flood of heterogeneous data and make it useful to scientists, powerful informatics systems are being put in place. The Cold Spring Harbor Laboratory/Wellcome Trust conference on genome informatics focused both on informatics technologies for data storage and processing as well as on the latest discoveries gained by analyzing genomic data.