Genetic Technology News

摘要

A Genome-Wide Linkage Analysis of Common Familial Colorectal Cancer; Novel Technology that Beats Immune Tolerance To Self-Antigens; GTN Strategic Partners; Some Important Patents for You To Check; GENETIC EVIDENCE IDENTIFIED FOR REGULATION OF MOLD'S RESISTANCE TO DRUGS: The incidence of potentially lethal infections caused by normally benign molds has increased immensely over the last two decades. Aspergillus fumigatus being a normally benign saprophytic fungus contains unique attributes that allow it to cause an often lethal invasive disease in immimocompromised patients, namely—invasive pulmonary aspergillosis (IPA). Till date, the mechanisms adopted by this opportunistic pathogen in survival and causing disease in immunocompromised hosts, especially organ transplant patients, are not fully reasonable. A. fumigatus causes substantial damage to host tissues during infection through invasive growth by hyphae and ensuing recruitment of immune effector cells. This type of infection generates significant inflammation and necrosis in lung tissues that can be visualized by histopathology experiments. Further, these pathogenic lesions likely represent regions of poor oxygen availability, otherwise called hypoxia to the pathogen and host.