Mitochondrial MIsCUes in liver regeneration

摘要

Beyond their well-known role as the energy factories of eukaryotic cells, mitochondria are also essential regulators of cell death. Interestingly, both processes are dependent on the concentration of Ca2+ within the mitochondrial matrix. It is thus predicted that manipulation of the expression or function of mitochondrial Ca2+ signaling proteins would have major consequences to cellular physiology including hepatocyte function. Indeed, Antony et al.