Mesoporous Silica SBA-15-supported Norephedrine and Ephedrine as Heterogeneous Chiral Ligands

摘要

Successful development of the homogeneous catalysts has been sometimes followed by attempts to attach the catalysts on an insoluble polymeric support.A suitably designed immobilized catalyst can retain the advantages of a heterogeneous catalyst in terms of simplified workup procedure and recyclization while maintaining reactivity and selectivity of a homogeneous catalyst.The immobilization of homogeneous species is of particular interest in the field of asymmetric catalysis since it is desirable to be able to regenerate and reuse expensive chiral catalysts.Polystyrene resin and silica gel have been most commonly used as insoluable supports for the immobilization of the catalysts.