Biological Synthesis of Polyketides from 6-n-Pentyl-alpha-pyrone by Streptomyces sp.

摘要

Selectivity is an essential requirement in synthetic organic chemistry.The regioselectivity of enzymes even on complex or symmetric molecules without any need of protecting groups is a fundamental strength of biocatalysis.Biocatalysis are also a powerful tool for the regioselective and enantio-selective synthesis of bioactive compounds,as well as for the generation of new,active,and less toxic derivatives for the bioactive natural products.