Isolation of Two New Meroterpenoids from Sargassum siliquastrum

摘要

In the course of our continuing phytochemical investigation of the algal genus Sargassum, we have recently published antioxidant and cytotoxic effects of organic extract of S. siliquastrum, leading to the isolation of several chromanol derivatives. Herein we report the isolation and structure determination of two new meroterpenoids (2, 3), together with one known compound (1) obtained on the reinvestigation of this extract. The isolated compounds have been tested in human cancer cell lines to assess their cytotoxic activity. The chemical structure of isolated compound (1) was identified as sargachromanol J by comparison of its NMR spectral data with those reported in the literature.