Synthesis of Carrier Free [~(32)P] 5-Chloro-8-Quinolyl Phosphate as a Phosphorylating Agent

摘要

The element phosphorus,a component of low molecular intermediate and nucleic acid,plays an important role in field of biology,genetics,chemistry and medical science.~(32)P and ~(33)P,pure beta emitters,have extensively been used in studies of biological mechanism and therapeutic agents.However,there has been much less attention for ~(32)P and ~(33)P labeled compounds and their application.It is because not much data are available in chemical reactions of phosphoric acid and its derivatives.