Dendrimer Encapsulated Pt Nanoparticle-Immobilized Glassy Carbon Electrode with High Electrocatalytic Redox Activity to Hydrogen Peroxide and Its Application for Biosensing

摘要

Dendrimers, which are highly-branched monodisperse macromolecules with well-defined size, shape, and surface functionality, have been widely used in the modification of electrode surfaces due to their good biocompatibility and adequate functional groups. The intriguing properties of dendrimers allow the dendrimer-coated surfaces to be utilized in a variety of fundamental and applied researches. For example, the use of dendrimers has been proposed for the design of microarray chips because dendrimer-immobilized surfaces provide a unique three-dimensional architecture with flexible branched arms connected to numerous functional groups. This allows for the effective immobilization of biomolecules with a high density as well as minimization of biomolecule denature. In addition, dendrimer-immobilized surfaces have been proven to be useful in improving sensitivity as well as selectivity for biosensing applications. Recently, we also reported facile surface modification of carbon-based materials with amine-terminated dendrimers and its applications to construct catalytic bifunctional surfaces for electrochemical reactions of chemicals such as hydrazine and oxygen.