2009/H1N1 infection in pregnancy association with adverse perinatal outcomes

摘要

Since identification of the 2009/H1N1 influenza virus, the increased risk of maternal morbidity and mortality from this novel infection has been highlighted.1 Past pandemics and seasonal flu have shown inconsistent perinatal effects. Some data have shown increased risk of preterm birth and fetal death.2 Other studies have indicated no increased fetal risk, supported by the absence of transplacental transmission of influenza virus in the umbilical cord sera of women with laboratory-confirmed flu infection.3 Studies evaluating the effect on perinatal outcomes during the 2009/H1N1 pandemic have tended to focus on maternal outcomes.