Problem-solving therapy reduces disability more than supportive therapy in older adults with major depression and executive dysfunction.

摘要

Question: Is problem-solving therapy (PST) better than supportive therapy (ST) for reducing disability in older adults with depression and executive dysfunction?Patients: 221 older adults (aged >59 years) with major non-psychotic depression (Structured Clinical Interview for Axis-I DSM-IV disorders), 24-item Hamilton Depression Rating Scale score >20, Mini-Mental State Examination score >24, Mattis Dementia Rating Scale initiation/preservation domain (DRS-IP) score <33 and Stroop Colour-Word Test score <25. Setting: Two research centres (Weill Cornell Medical College and University of California at San Francisco), USA; 2002-2007.