Relapse with oral antipsychotics versus long-acting injectable antipsychotics: New paradoxical findings

摘要

Earlier randomised controlled trials (RCTs) for first-generation antipsycho-tics (FGA) comparing long-acting injectable antipsychotics (LAIs) to oral antipsychotics (OAPs) suggested FGA-LAIs were superior at preventing relapse. By delivering a full-recommended dose on a continuous basis, LAIs would seem to overcome adherence issues associated with OAPs.