Magnetically Recoverable CuFe_2O_4 Nanoparticles: Catalyzed Synthesis of Aryl Azides and 1,4-Diaryl-1,2,3-triazoles from Boronic Acids in Water

摘要

Magnetically recoverable and reusable CuFe_2O_4 nanoparticles are shown to be highly efficient catalysts for the onepot synthesis of biologically important 1,4-diaryl-1,2,3-triazoles starting from boronic acids, sodium azide, and acetylenes. The use of aqueous reaction medium at room tempera- ture, the low cost and facile recovery of the catalyst by application of an external magnetic field, and consistently high catalytic efficiency for at least three consecutive cycles renders the protocol operationally attractive.