Self-Terminating Radical Oxygenations: Probing of the Scope of the Concept by Use of Various Organic O-Centered Radicals

摘要

Addition of various organic O-centered radicals XO~·{i.e.(alkoxycarbonyl)oxyl radicals, ROC(O)O~·,[(alkoxycarbonyl)-acyl]oxyl radicals, ROC(O)C(O)O~·(carbamoyl)oxyl radicals, R_2NC(O)O~·, alkoxyl radicals, RO~· and nitroxyl radicals, R_2NO~·} to alkynes initiates an oxidative radical cyclization cascade, which is terminated by release of a C- or N-centered radical X~·. This finding clearly highlights are generality of the recently discovered concept of self-terminating radical oxygenations, through which C ident to C triple bonds may be converted into carbonyl groups under very mild reaction conditions.