Convenient RCM-Mediated Synthesis and Spectroscopic Study of Novel Ferrocenyl-Substituted 2,5,8,9-Tetrahydro-3H-imidazo[1,2-a][1,3]diazepin-3-ones

摘要

The ferrocene-containing N-BOC-protected 1-allyl-2-(allyl-amino)imidazolones 5 and 13 were transformed into mono- and bis(2,5,8,9-tetrahydro-3H-amidazo-[1,2-a][1,3]diazepin-3-ones) 7 and 15 in a ring-closing metathesis (RCM) reaction using Grubbs' catalyst [RuCl_2 (CHPh){P(cyclo-C_6H_(11))_3}_2]. The structures of the novel compounds were identified by IR and multinuclear NMR spectroscopy.