Synthetic scheme for the preparation of ~(13)C-labeled 2,7-dimethylocta-2,4,6-triene-1,8-dial, the central part of carotenoids

摘要

Starting from acetic acid and methyl iodide an efficient modular synthetic scheme has been developed for the synthesis of ~(13)C-labeled 2,7-dimethylocta-2,4,6-triene-1,8-dial, which is a suitable building block in the synthesis of carotenoids with tenfold ~(13)C-enrichment in the central part.