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Cross-coupling reactions of aryl halides with amines, phenols, and thiols catalyzed by an N,N′-dioxide-copper(I) catalytic system

机译:N,N'-二氧化物-铜(I)催化体系催化芳基卤化物与胺,酚和硫醇的交叉偶联反应

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摘要

The coupling reactions of various N, O, and S nucleophilic reagents with aryl halides have been successfully carried out under mild conditions by using a novel chiral N,N′-dioxide-copper(I) catalytic system as the catalyst. This versatile and efficient catalyst system has been demonstrated to facilitate the cross-coupling reactions of aryl halides with amines, phenols, and thiols to afford the corresponding desired products in good to excellent yields.
机译:通过使用新型手性N,N'-二氧化物-铜(I)催化体系,在温和条件下已成功进行了各种N,O和S亲核试剂与芳基卤的偶联反应。已经证明了这种通用且有效的催化剂体系可促进芳基卤化物与胺,酚和硫醇的交叉偶联反应,从而以良好或优异的收率提供相应的所需产物。

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