Long-term symptomatic group B streptococcal vulvovaginitis: eight cases resolved with freshly cut garlic.

摘要

We found that neither an accepted diagnostic definition nor a treatment has been established for group B streptococcal (GBS) vulvovaginitis. A review of the literature revealed five previous articles describing a combined total of 26 cases of GBS vaginitis in the absence of other pathogens [1-5]. GBS vulvovaginitis presents with complaints of vulvar burning and clear or white vaginal discharge. The labia appear fiery-red, sometimes with fissures. It has been reported in both celibate and non-celibate women. Cultures contain GBS at a high multiplicity: > 100,000,000 colony-forming units (CFU)/g of vaginal fluid or ++++ growth and decreased lactobacillus. GBS vaginitis is sometimes identified as aerobic vulvovaginitis. High colonization with GBS appears to provoke the release of cytokines causing inflammation and a severe decrease in lactobacillus. Current first-line treatment is oral penicillin or clindamycin. It was first noticed in 1976 in an original article in the American Journal of Obstetrics and Gynecology entitled "Antibiotic Treatment of Parturient Women Colonized With GBS" that oral antibiotics were ineffective at permanently decreasing asymptomatic GBS vaginal colonization.