Invasive choriocarcinoma involving the major duodenal papilla.

摘要

Choriocarcinoma is a highly malignant tumor that most commonly arises from the gestational trophoblastic tissue in women. The essential components of choriocarcinoma are malignant cytotrophoblasts and syncytiotrophoblasts. Extragenital, nongestational choriocarcinoma is uncommon; the majority arise in midline structures, such as the brain, the mediastinum, the esophagus, the retroperitoneum,and the bladder. Such tumors also may arise in non-midline organs, such as the stomach, the small intestine, the colon, the lung, the kidney, and the liver; most non-midline choriocarcinomas have occurred in men. The present case is the first reported of a retroperitoneal choriocarcinoma invading the duodenum that presented as GI hemorrhage. Radiotherapy and thalidomide were used for palliation.