SYNTHESIS AND STRUCTURE OF 5,7-DIMETHYLTHIENO3,4-dPYRIDAZINE

摘要

The reaction of 2,5-dimethylthiophene-3,4-dicarboxaldehye with excess hydrazine hydrate afforded the desired 5,6-fused ring thiophene derivative, 5,7-dimethylthieno3,4-dpyridazine, in high yield (82). Pyridazine 4 was characterized spectroscopically and its structure was confirmed by X-ray crystallography. Compound 4 was observed to have an inverted, coplanar stacking arrangement in the solid state.