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Advances in Anti-Viral Therapeutics

机译:抗病毒治疗的进展

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Hepatitis C virus (HCV) and HIV infections are of high economical importance as they have a global impact,high mortality rates and,consequently novel treatments are urgently needed.Worldwide,170 and 34-46 million people are infected with HCV and HIV,respectively.HCV and HIV medications constitute the largest antiviral markets today.The efforts in fighting HCV infections are still limited to early clinical development,trying to establish proof-of-concept in man.However,in HIV,there is a better chance that some of the new drugs on new and old targets (indirect and direct antiviral targets,like CCR5 and HIV protease,respectively) will finally reach the market.
机译:丙型肝炎病毒(HCV)和HIV感染对全球具有影响,死亡率高,因此迫切需要新颖的治疗方法,因此在经济上具有重要的经济意义。全世界分别有170和34-46百万人感染HCV和HIV HCV和HIV药物构成了当今最大的抗病毒药物市场。与HCV感染作斗争的努力仍仅限于早期临床开发,试图在人体内建立概念验证。然而,在HIV中,某些人有更好的机会靶向新旧靶标的新药(分别为间接和直接抗病毒靶标,如CCR5和HIV蛋白酶)将最终投放市场。

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