Pharmacokinetics and clinical evaluation of the alogliptin plus pioglitazone combination for type 2 diabetes

Scheen Andre J.

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Pharmacokinetics and clinical evaluation of the alogliptin plus pioglitazone combination for type 2 diabetes

机译：阿格列汀联合吡格列酮治疗2型糖尿病的药代动力学和临床评价

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Introduction: Type 2 diabetes is a complex disease with multiple defects, which generally requires a combination of several pharmacological approaches to reach glucose control targets. A unique fixed-dose combination combines a thiazolidinedione (pioglitazone) and a dipeptidyl peptidase-4 inhibitor (alogliptin).

机译：简介：2型糖尿病是一种具有多种缺陷的复杂疾病，通常需要结合几种药理学方法才能达到血糖控制目标。独特的固定剂量组合结合了噻唑烷二酮（吡格列酮）和二肽基肽酶-4抑制剂（阿格列汀）。

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《Expert opinion on drug metabolism & toxicology》 |2015年第6期|共16页
作者
Scheen Andre J.;
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正文语种 eng
中图分类药学;
关键词
alogliptin; combined therapy; fixed-dose combination; pharmacokinetics; pioglitazone; type 2 diabetes mellitus;

机译：阿格列汀;联合治疗;固定剂量联合;药代动力学;吡格列酮;2型糖尿病;
入库时间 2022-08-18 11:02:29

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1. Pharmacokinetics and clinical evaluation of the alogliptin plus pioglitazone combination for type 2 diabetes [J] . Scheen Andre J. Expert opinion on drug metabolism & toxicology . 2015,第6期

机译：阿格列汀联合吡格列酮治疗2型糖尿病的药代动力学和临床评价
2. The effect of alogliptin and pioglitazone combination therapy on various aspects of β-cell function in patients with recent-onset type 2 diabetes [J] . Dani?l H Van Raalte, Renate E van Genugten, Bj?rn Eliasson, European journal of endocrinology . 2014,第4期

机译：阿格列汀联合吡格列酮对新发2型糖尿病患者β细胞功能各方面的影响
3. Alogliptin in combination with metformin and pioglitazone for the treatment of type 2 diabetes mellitus [J] . Daniel Q Holland, Joshua J Neumiller Diabetes, metabolic syndrome and obesity: targets and therapy . 2014,第3a2期

机译：阿格列汀联合二甲双胍和吡格列酮治疗2型糖尿病
4. Evaluation of treatment regimens for blood glucose regulation in type II diabetes using pharmacokinetic-pharmacodynamic modeling [C] . Ekram Fatemeh, Barazandegan Melissa, Kwok Ezra, Chinese Control Conference . 2015

机译：使用药代动力学-药效学模型评估II型糖尿病患者血糖调节的治疗方案
5. Evaluation of the effectiveness of Sertoli cells to suppress immune responses for the potential use as a safer alternative to systemic immune suppression in clinical islet transplantation for the treatment of type 1 diabetes [D] . Lord, Sarah Jean 2005

机译：评价血液细胞抑制免疫应答的潜在用途的潜在用途，作为临床胰岛移植在临床胰腺移植中的含有型1型糖尿病的替代品
6. Fixed-dose combination of alogliptin/pioglitazone improves glycemic control in Japanese patients with type 2 diabetes mellitus independent of body mass index [O] . Chie Aoki, Kunihiro Suzuki, Hisamoto Kuroda, 2017

机译：与体重指数无关的阿格列汀/吡格列酮固定剂量组合可改善日本2型糖尿病患者的血糖控制
7. PDB25 Evaluation Of The Pharmacy Budget Impact Of Alogliptin Plus Pioglitazone Fixed Dose Combination In The Treatment Of Type-2 Diabetes Mellitus [O] . Bron M., Ferrufino C.P., Samyshkin Y., 2013

机译：PDB25评价阿格列汀加吡格列酮固定剂量联合治疗2型糖尿病的药房预算

Pharmacokinetics and clinical evaluation of the alogliptin plus pioglitazone combination for type 2 diabetes

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