Secondary IGF-I Deficiency as a Prognostic Factor of Growth Hormone (GH) Therapy Effectiveness in Children with Isolated, Non-acquired GH Deficiency

Smyczynska J.; Stawerska R.; Hilczer M.; Lewinski A.

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Secondary IGF-I Deficiency as a Prognostic Factor of Growth Hormone (GH) Therapy Effectiveness in Children with Isolated, Non-acquired GH Deficiency

机译：继发性IGF-I缺乏症是孤立，未获得性GH缺乏症儿童生长激素（GH）治疗效果的预后因素

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Objective: Growth hormone (GH) deficiency (GHD) has recently been classified as secondary IGF-I deficiency but the significance of IGF-I measurement in diagnosing GHD is still discussed. The aim of the study was to assess the relationships between IGF-I secretion and GH therapy effectiveness in children with GHD.

机译：目的：生长激素（GH）缺乏症（GHD）最近已被列为继发性IGF-I缺乏症，但仍在探讨IGF-I测量在诊断GHD中的意义。该研究的目的是评估GHD儿童的IGF-I分泌与GH治疗效果之间的关系。

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《Experimental and clinical endocrinology and diabetes: Official journal, German Society of Endocrinology [and] German Diabetes Association》 |2015年第4期|共6页
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Smyczynska J.; Stawerska R.; Hilczer M.; Lewinski A.;
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正文语种 eng
中图分类内分泌腺疾病及代谢病;
关键词
short stature; growth hormone stimulation tests; insulin-like growth factor-I; recombinant human growth hormone; final height;

机译：身材矮小;生长激素刺激试验;胰岛素样生长因子-I;重组人生长激素;最终身高;

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1. Secondary IGF-I Deficiency as a Prognostic Factor of Growth Hormone (GH) Therapy Effectiveness in Children with Isolated, Non-acquired GH Deficiency [J] . Smyczynska J., Stawerska R., Hilczer M., Experimental and clinical endocrinology and diabetes: Official journal, German Society of Endocrinology [and] German Diabetes Association . 2015,第4期

机译：继发性IGF-I缺乏症是孤立，未获得性GH缺乏症儿童生长激素（GH）治疗效果的预后因素
2. Basal characteristics and first year responses to human growth hormone (GH) vary according to diagnostic criteria in children with non-acquired GH deficiency (naGHD): observations from a single center over a period of five decades [J] . Michael B.Ranke, RolandSchweizer, GerhardBinder Journal of pediatric endocrinology & metabolism: JPEM . 2018,第11期

机译：基础特征和对人体生长激素（GH）的第一年反应根据有未获得的GH缺乏的儿童诊断标准（NAGHD）：在五十年内的单一中心观察
3. Head circumference in untreated and IGF-I treated patients with Laron syndrome. Comparison with untreated and hGH-treated children with isolated growth hormone deficiency. [J] . LaronZ., IluzM., KauliR. Growth hormone and IGF research: Official journal of the Growth Hormone Research Society and the International IGF Research Society . 2012,第2期

机译：未经治疗和IGF-I治疗的Laron综合征患者的头围。与未治疗的和生长激素治疗的患儿孤立生长激素缺乏症的比较。
4. Isolated Growth Hormone Deficiency Type 2: From Gene to Therapy [C] . Maria Consolata Miletta, Didier Lochmatter, Vibor Pektovic, European Society of Pediatric Endocrinology Advanced Seminar in Developmental Endocrinology . 2012

机译：分离的生长激素缺乏型2：从基因到治疗
5. Uncovering Novel Genes Causing Isolated Gonadotropin Releasing Hormone Deficiency Using Runs of Homozygosity in Outbred Families [D] . Kutateladze, Anna. 2018

机译：使用纯合子在近亲家庭中发现导致分离的促性腺激素释放激素缺乏的新基因
6. Relationship between IGF-I Concentration and Metabolic Profile in Children with Growth Hormone Deficiency: The Influence of Childrens Nutritional State as well as the Ghrelin Leptin Adiponectin and Resistin Serum Concentrations [O] . Renata Stawerska, Joanna Smyczyńska, Maciej Hilczer, 2017

机译：生长激素缺乏症儿童的IGF-I浓度与代谢特征之间的关系：儿童营养状况以及GhrelinLeptinAdiponectin和Resistin血清浓度的影响
7. Growth hormone (GH) peak in stimulation tests and the severity of IGF-I deficiency before treatment as the predictors of GH therapy effectiveness in children with short stature [O] . Joanna Smyczyńska, Renata Stawerska, Andrzej Lewiński, 2016

机译：刺激试验中的生长激素（GH）峰值和IGF-I缺乏的严重程度作为治疗前的预测因子，患儿患儿患儿矮小

Secondary IGF-I Deficiency as a Prognostic Factor of Growth Hormone (GH) Therapy Effectiveness in Children with Isolated, Non-acquired GH Deficiency

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