Association of the Renal Resistive Index with Microvascular Complications in type 2 Diabetic Subjects

摘要

Chronic complications are the leading causes of morbidity and mortality in the diabetic population. The intrarenal resistive index ( RI) has been reported to be increased in hypertensive subjects with microalbuminuria and limited data is present for diabetic subjects. 101 subjects with Type 2 Diabetes Mellitus were included in the study. We grouped the study population according to the urinary albumin excretion ( UAE). Group 1: UAE < 30 mg/ day ( n = 36); Group 2: UAE 30- 300 mg/ day ( n: 37); Group 3: UAE > 300 mg/ day ( n: 28). We also grouped the study population according to the intrarenal RI value. Group consisted of subjects with RI = 0.70 and group II < 0.70. The mean intrarenal RI values of patients in group 3 were higher than those of group 1 and group 2 ( 0.72 vs. 0.69 p = 0.048; 0.72 vs. 0.69; p = 0.048 respectively). The duration of diabetes, hip circumference, and hs- CRP levels were statistically significantly higher in subjects with intrarenal RI = 0.70 compared to those with intrarenal RI < 0.70 ( p: < 0.001, 0.048 and 0.0148 respectively). Presence of retinopathy and neuropathy was statistically significantly higher in subjects with intrarenal RI = 0.70 compared to those with intrarenal RI < 0.70. RI may predict the development of microvascularcomplications in diabetic subjects.