首页> 外文期刊>Experimental and clinical endocrinology and diabetes: Official journal, German Society of Endocrinology [and] German Diabetes Association >Prevalence of cardiovascular disease and risk factors in the Chinese population with impaired glucose regulation: The 2007-2008 China National diabetes and metabolic disorders study
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Prevalence of cardiovascular disease and risk factors in the Chinese population with impaired glucose regulation: The 2007-2008 China National diabetes and metabolic disorders study

机译:中国血糖调节受损人群中心血管疾病的流行和危险因素:2007-2008年中国糖尿病和代谢性疾病研究

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Aims: Cardiovascular disease (CVD) is one of the most common chronic diseases in China. This aim of this study is to determine the prevalence of CVDs and risk factors in Chinese impaired glucose regulation subjects. Methods: We used a multistage, stratified sampling method to select subjects from the general Chinese population aged 20 years and older. Subjects underwent an oral glucose tolerance test to identify normal glucose tolerance (NGT) and impaired glucose regulation including isolated impaired fasting glucose (i-IFG), impaired glucose tolerance (i-IGT), and combined IFG/IGT and diabetic mellitus (DM). A logistic regression analysis was performed to examine the association between glucose abnormalities and CVD events. Results: We identified that 34 293 subjects had NGT, 1 469 i-IFG, 4 571 i-IGT, 957 IFG/IGT and 4 949 DM. The age-sex standardized prevalence rate of cardiovascular disease was 1.06% (95% CI 0.87-1.28), 1.79% (95% CI 1.37-2.33) and 3.83% (95% CI 2.79-5.24) in NGT, impaired glucose regulation and DM, respectively. Among impaired glucose subjects, prevalence of defined CVD risk factors (smoking, overweight, obesity, hypertension and dyslipidemia) was 29.52% (95% CI: 27.8-31.21), 36.25% (95% CI: 34.29-38.26), 10.05% (95% CI: 8.86-11.37), 36.43% (95% CI: 34.53-38.36) and 69.96% (95% CI: 67.87-71.98), respectively. Compared to 1 risk factor, the odds ratios (ORs) of CVDs with 2, 3 or 4 risk factors were 1.94 (95% CI: 0.74-5.09), 2.76 (95% CI: 1.06-7.21) and 5.84 (95% CI: 1.68-20.26), respectively. Additionally, compared to i-IFGs, ORs of CVDs with i-IGT and IFG/IGT were 2.88 (95%CI 1.36-6.01) and 2.12 (95% CI 0.83-5.44), respectively. Conclusion: The prevalence of cardiovascular risk factors was high in the Chinese impaired glucose regulation population. The postprandial hyperglycemia is more associated with CVD than isolated fasting hyperglycemia.
机译:目的:心血管疾病(CVD)是中国最常见的慢性疾病之一。这项研究的目的是确定中国葡萄糖调节受损的人群中CVD的患病率和危险因素。方法:我们采用了多阶段,分层抽样的方法,从20岁以上的中国普通人群中选择受试者。受试者进行了口服葡萄糖耐量测试,以确定正常的葡萄糖耐量(NGT)和葡萄糖调节受损,包括孤立的空腹血糖(i-IFG),葡萄糖耐量受损(i-IGT)以及IFG / IGT和糖尿病合并(DM) 。进行逻辑回归分析以检查葡萄糖异常与CVD事件之间的关联。结果:我们确定34 293名受试者患有NGT,1 469 i-IFG,4 571 i-IGT,957 IFG / IGT和4 949 DM。 NGT,血糖调节和功能受损的年龄性别标准化心血管疾病患病率分别为1.06%(95%CI 0.87-1.28),1.79%(95%CI 1.37-2.33)和3.83%(95%CI 2.79-5.24)。 DM,分别。在葡萄糖受损的受试者中,明确的CVD危险因素(吸烟,超重,肥胖,高血压和血脂异常)的患病率分别为29.52%(95%CI:27.8-31.21),36.25%(95%CI:34.29-38.26),10.05%( 95%CI:8.86-11.37),36.43%(95%CI:34.53-38.36)和69.96%(95%CI:67.87-71.98)。与1个危险因素相比,具有2、3或4个危险因素的CVD的优势比(OR)为1.94(95%CI:0.74-5.09),2.76(95%CI:1.06-7.21)和5.84(95%CI) :1.68-20.26)。此外,与i-IFG相比,使用i-IGT和IFG / IGT的CVD的OR分别为2.88(95%CI 1.36-6.01)和2.12(95%CI 0.83-5.44)。结论:中国血糖调节受损人群的心血管危险因素高发。餐后高血糖比单纯的空腹高血糖与CVD的关系更大。

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