Study of proliferation and 3D epidermal reconstruction from foreskin, auricular and trunk keratinocytes in children

摘要

Objective: Severe burns in children are conventionally treated with split-thickness skin autografts or epidermal sheets. An alternative approach is to graft isolated keratinocytes. We evaluated foreskin and other anatomic sites as donor sources for autologous keratinocyte graft in children. We studied in intro capacities of isolated keratinocytes to divide and reconstitute epidermal tissue.